Chaperones come of age

Csaba Söti; Péter Csermely

doi:10.1379/1466-1268(2002)007<0186:CCOA>2.0.CO;2

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Csaba Söti,¹ Péter Csermely^1,2

¹aDepartment of Medical Chemistry, Semmelweis University, PO Box 260, H-1444 Budapest, Hungary
²bBiorex R&D Co, PO Box 361, H-8201 Veszprém, Hungary

Abstract

Chaperone function plays a key role in repairing proteotoxic damage, in the maintenance of cell architecture, and in cell survival. Here, we summarize our current knowledge about changes in chaperone expression and function in the aging process, as well as their involvement in longevity and cellular senescence.

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Csaba Söti and Péter Csermely "Chaperones come of age," Cell Stress & Chaperones 7(2), 186-190, (1 April 2002). https://doi.org/10.1379/1466-1268(2002)007<0186:CCOA>2.0.CO;2

Received: 4 October 2001; Accepted: 1 January 2002; Published: 1 April 2002

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